in spite of:notwithstanding

If you expect danger form the front, face it, do not put yourself at a disadvantage by keep looking over your shoulder

老虎入山洞,顾前不顾后

turn one's back on

对…掉头不顾，轻视

in spite of

不管,不顾,尽管,虽然

a cynical disregard for others' safety

只顾自己不顾他人安危的可耻行为

At present there are quite a few cadres who ignore the people's livelihood and couldn't care less about their sufferings.

现在，不顾人民生活，不顾人民死活的干部还不少。

fire-fighters working with a complete disregard of their own safety

奋不顾身的消防队员.

He would stick at nothing to get his own way.

他不顾一切，一意孤行。

He did it quite without regard to the results.

他做这事绝不顾及结果。

They kept going in spite of their fears.

他们不顾害怕继续前进

continues to work regardless.

不顾后果地继续工作

drive without regard for/to speed limits

不顾速度限制开快车

He rushed forward in contempt of danger.

他不顾危险冲向前去。

One must not think only of the present and neglect the future.

不能只顾现在，不管将来。

Who takes care of the elderly when they are no longer able to care for themselves?

当老人不能照顾自己时，谁来照顾他们？

Both must be taken into consideration and it is wrong not to do so.

两者必须兼顾，不兼顾是错误的。

The dissatisfied customer Berated the florist

不满意的顾客责骂花商。

have, pay, show little regard for the feelings of others

不大顾及别人的感情.

Let's set aside my personal feelings.

不必顾及我个人的感情.